Dysregulated R-loops can cause stalled replication forks and telomere instability. However, how R-loops are recognized and regulated, is still not well understood, particularly at telomeres.
Healthy cells respond appropriately to changes in their environment. They do this by sensing what's happening outside and relaying a command to the precise biomolecule in the precise domain that can carry out the necessary response.
Researchers tracked bird diversity in public parks and private backyards in twin cities in Illinois with significantly different development histories and green space management practices. They found that birds rely on both public and private spaces in different seasons and for
A study conducted over a period of 14 years in the Brazilian savanna-like biome shows its typical vegetation rapidly becoming "cerradão"—a biodiversity-poor forest formation—while resistance to drought and wildfires weakens.
Several types of conventional cancer therapies, such as radiotherapy or chemotherapy, destroy healthy cells along with cancer cells. In advanced stages of cancer, tissue loss from treatments can be substantial and even fatal. Cutting-edge cancer therapies that employ
Researchers have created scaffolds with enhanced strength by fabricating 20 vol% polydopamine-modified nano hydroxyapatite (pDA-nHA), featuring a distinctive lamellar structure. These scaffolds were then immersed in a polyetherketoneketone (PEKK) synthesis system for
A large number of coal pillars were left behind during the mining of multi-coal seams. These pillars, when unstable, pose significant risks during both production and well closure stages in coal mines. Their failure can exert intense dynamic pressure on lower coal seams,
The European Court of Human Rights is "backsliding" by surreptitiously reversing its principles established to protect asylum seekers, a new study says.
The fierce competition between China and the United States of America for control of emerging technologies such as AI and 5G will determine the international balance of power, a new study says.
In the United States, the number of so-called progressive prosecutors focused on criminal justice reform has risen, but few studies have addressed the relation between these prosecutors' policies and crime rates. In a new study, researchers examined whether progressive
Criminal legal system contact has emerged as a key event for understanding family life, childhood well-being, and patterns of inequality. Scholars have found many problems for families that are linked to mass criminalization and effects tend to be concentrated among the most
Researchers have unveiled a method capable of detecting drug substances from fingerprints lifted from crime scenes, which could provide fresh insights into unsolved cases. The research is published in the journal Drug Testing and Analysis.
Serious wine drinkers often have their preferences: Some prefer sweet hints of chocolate in a Malbec from Argentina, while others are drawn to a spicy and fruity Cabernet Sauvignon from Napa Valley. Wine connoisseurs firmly believe that the soil in which grapes are grown
As the global demand for high-quality tomatoes continues to rise, researchers have unveiled findings on the optimal spacing of grafted "Primo Red" tomatoes within high tunnel systems. The study offers important insights into enhancing yield and quality for tomato producers
Researchers have developed a method to use an image generation AI model to create realistic images of single cells, which are then used as 'synthetic data' to train an AI model to better carry out single-cell segmentation.
Oases are important habitats and water sources for dryland regions, sustaining 10% of the world's population despite taking up about 1.5% of land area. But in many places, climate change and anthropogenic activities threaten oases' fragile existence. New research shows how the
Normally, a person's pupils naturally widen (or dilate) in low-light environments to allow more light into the eye. However, in a new study, researchers reported that a person's pupils also dilate when they are concentrating on tasks. In particular, they found that the more a
A group of around 40 scientists signed a declaration calling for formal acknowledgement of consciousness in a range of animals, including insects and fish – but the evidence is still lacking
Understanding the relationship between mitochondrial DNA (mtDNA) and animal growth could provide valuable information for selective breeding in aquaculture. However, the complex interactions between genetics and environmental factors often hinders progress in this field. To
In the 1930s, the United States government introduced redlining, a discriminatory practice that categorized neighborhoods based on people's race or ethnicity and denied financial services to residents in certain areas—redlining disproportionately affected marginalized
In a first demonstration of "electron videography," researchers have captured a microscopic moving picture of the delicate dance between proteins and lipids found in cell membranes. The technique can be used to study the dynamics of other biomolecules, breaking free of
Pyrrolizidine alkaloids are as bitter and toxic as they are hard to pronounce. They're produced by several different types of plants and are among the leading causes of accidental death in cattle.