New strategy to precisely target subtypes of key protein

Cyclosporine is one of the most common and effective immunosuppressant drugs used to treat chronic diseases like arthritis and psoriasis, but it comes with a risk of serious side effects. Scientists think that may be because the drug broadly targets cyclophilins, a family of 17

Two rare super-Mercuries discovered in the same star system

While observing the star system HD 23472 with the ESPRESSO spectrograph (ESO), a team led by Instituto de Astrofísica e Ciências do Espaço's (IA3) researcher Susana Barros (IA & Dep. de Física e Astronomia—Faculdade de Ciências da Universidade do Porto), found three

Evidence of the use of baby carriers 10,000 years ago

It seems logical enough: even in their earliest history, humans must have needed something to carry their babies around in as they moved from place to place. But because little hard evidence of this exists—no infant-sling fabrics discernible in archeological digs, and very few

New 'triggers' in an essential pathway to destroy microRNAs

In a study from the lab of Whitehead Institute Member David Bartel, researchers have identified genetic sequences that can lead to the degradation of cellular regulators called microRNAs in the fruit fly Drosophila melanogaster. The findings were published September 22 in

New understanding of the inner world of lysosomes

Researchers at Duke-NUS Medical School and colleagues in Singapore have identified a protein that transports degraded membrane lipids out of lysosomes, cellular organelles that are the breakdown factories of cells. The findings, published in the Proceedings of the National

New upcycling system for commercial polyesters

While plastics or synthetic polymers have many useful properties, their mismanagement has resulted in widespread pollution that chokes up our ecosystems. As a solution to this, many synthetic polymers are sent for reprocessing and recycling; polyethylene terephthalate (PET) is

The geologic secrets of Lake Mead

As the climate crisis continues to affect the American West, sunken boats and human remains aren't the only surprises to be revealed by record-low water levels at Lake Mead. Sedimentary rocks that hadn't been seen since the 1930s are now exposed along the constantly changing