Drugs that act on NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment consciousness, are key for treating neuropsychiatric disorders. These drugs were developed based on the assumption that the proportion of calcium in the
The 153,074 job cuts from last month marked a 175% jump from the same month a year ago and a 183% spike from September, according to a new report.
UNITED NATIONS (Reuters) -The United Nations Security Council removed sanctions on Syrian President Ahmed al-Sharaa, who is due to meet U.S. President Donald Trump at the White House on Monday. The U.S.-drafted resolution on Thursday also lifted sanctions on Syrian Interior
JERUSALEM (Reuters) -An Israeli hostage who was released in October has told an Israeli television channel he was subjected to sexual violence during his two-year captivity in Gaza by Palestinian militants -- the first male hostage to publicly make such an accusation. Rom
Ethan Hawke had a memorable first visit to Miami on Nov. 2, where he accepted the Miami Film Festival’s Variety Virtuoso Award and sat down with Variety‘s co-editor-in-chief Ramin Setoodeh for a discussion about his long and illustrious career. The actor-producer discussed his
“Wicked” fans can find themselves back in Oz with the premiere of “Wicked: One Wonderful Night,” a musical special co-hosted by Ariana Grande and Cynthia Erivo on Thursday night. Following the events of “Wicked,” “Wicked: One Wonderful Night” will offer audiences the
Plant protection products protect crops from pests, diseases and weeds. However, many of the fungicides, herbicides and insecticides also have a negative effect on terrestrial and aquatic organisms such as pollinators or fish that are not the primary target of their use. How
Bad Brain was founded in August 2023, but NetEase opted to end its partnership with the studio just two years later.
Silversun Pickups have a new album on the way. Tenterhooks , the follow-up to 2022’s Physical Thrills , arrives in February via the band’s own New Machine Recordings, and lead single “The Wreckage” is out today.
The United Nations Security Council voted in favor of a US resolution on Thursday to lift sanctions on Syrian President Ahmed al-Sharaa, ahead of his White House visit next week. "(The Council) decides that Ahmed al-Sharaa...and (Interior Minister) Anas Hasan Khattab are
Rep. Marjorie Taylor Greene (R-Ga.) said Thursday she is “very impressed” with former Speaker Nancy Pelosi’s (D-Calif.) “ability to get things done” after she announced she will not seek reelection. “I will praise Nancy Pelosi, she had an incredible career for her party,”
Low Skilled Workers Are a Myth . “[Minimum wage jobs] are not low-skill. They simply require different skills, ones that not just anyone possesses.” 💬 Join the discussion on kottke.org →
A third of fans who watch the NBA think players or coaches are involved in illegal activity by influencing the outcome of games or individual performance to affect sports gambling results, according to a new survey. The latest Quinnipiac University poll found that 33 percent of
The actor stars alongside Elizabeth Olsen and Callum Turner in the A24 afterlife-set film.
Signed by 45 countries and the European Union as of 2019, the Council of Europe treaty is meant to standardise support for women who are victims of violence, including domestic abuse.
The Supreme Court on Thursday ruled President Trump’s State Department can prohibit transgender Americans from listing their gender identity on their passports, for now. It hands another legal victory for Trump in his efforts to eviscerate what his administration calls “gender
Presented by Panasonic — COP30, the 2025 United Nations Climate Change Conference that kicks off Monday in Belém, Brazil, is an annual gathering of nations to work on the future of climate action. {beacon} Energy & Environment Energy & Environment The Big Story US absence
Gilson Lavis, the longtime drummer for Squeeze and Jools Holland’s Rhythm And Blues Orchestra, has died. Holland reported the news in a post to his social media accounts today. Lavis passed away at home Wednesday in Lincolnshire. No cause of death has been provided. He was 74.
Anthracnose is considered one of the most significant diseases affecting olive trees. Popularly known as "soapy olive" due to the appearance of fruit affected by it, this disease, caused by various fungal species of the genus Colletotrichum, significantly reduces yields and
A research team led by Prof. Li Xiangxian from the Anhui Institute of Optics and Fine Mechanics, the Hefei Institutes of Physical Science of the Chinese Academy of Sciences, has developed a new deep learning model that significantly enhances both the accuracy and
Sen. Bernie Sanders (I-Vt.) said Wednesday that New York City Mayor-elect Zohran Mamdani is a new leader of the Democratic Party by virtue of winning his race on Tuesday. In an interview on CNN’s “The Source,” anchor Kaitlan Collins asked the progressive senator whether he
An international team of researchers has discovered three new, bizarre, and wart-covered species of tree toads from Tanzania that give birth to fully developed toadlets. A key element of the study was the examination of specimens housed in the wet collection of the Museum für
JPMorgan Chase CEO Jamie Dimon on Wednesday said his company will not donate money toward the White House's ballroom construction, where the East Wing once stood. In an interview with Dimon, CNN anchor Erin Burnett noted how JPMorgan Chase was not listed among the companies
Emmylou Harris and Buddy Miller seem like birds of an eternal feather, having played together frequently over the decades, but there is a first time for everything. And for these two, that first time was the tour Harris did with Miller supporting her on guitar that is
A24 has acquired the rights to Overcooked, Deadline reports.
We've curated everything you need to be named Best Gift Giver of the Year. Do stories and artists like this matter to you? Become a Colossal Member today and support independent arts publishing for as little as $7 per month. The article The Colossal Shop’s 2025 Gift Guide:
A study from St. Jude Children's Research Hospital uncovered an alternative binding pocket within nuclear receptors, revealing a much-needed new therapy route for this important class of drug targets. The scientists found the "hidden" pocket on the pregnane X receptor (PXR), a
The Detroit three, which includes Ford, GM and Chrysler-parent Stellantis, have rolled back their ambitious plans for EVs, pivoting to their gasoline-powered models.
A comprehensive Hungarian study has revealed that the behavior of pharmaceutical residues in soil does not depend on a single factor, but is shaped by several interacting processes. The researchers emphasized that, based on their findings, it would be worth revising current
Sounds can alter the way the brain interprets what it sees. This is the key finding of a new study by SISSA researchers in Trieste, published in PLOS Computational Biology. The research shows that, when sounds are paired with moving visual stimuli, the latter are perceived
Kelvin Yu has inked a multi-year overall deal with Sony Pictures Television, Variety has learned exclusively. Under the deal, Yu will develop and produce scripted comedy, drama, and animated series for the independent studio. “I’ve had the privilege of working with Kelvin, and
At its deepest physical foundations, the world appears to be nonlocal: particles separated in space behave not as independent quantum systems, but as parts of a single one. Polish physicists have now shown that such nonlocality—arising from the simple fact that all particles of
The president of Moldova urges the European Union to find “creative” solutions to break the impasse and speed up its membership to the EU.
A new study led by researchers at the Lamont-Doherty Earth Observatory offers the clearest evidence yet that a centuries-long drought transformed life on Rapa Nui (Easter Island) beginning around the year 1550.
The EU antitrust enforcer is investigating a potential agreement between the two stock exchange groups for derivatives, arguing it may be in breach of European rules designed to spur competition in the EU market.
Black–white inequality declined during much of the 20th century, as measured by wages and intergenerational mobility. Scholars have attributed this to a variety of reasons, most notably Black migration and increases in Black people's education levels.
The Future Class cohort was both an award and an incubator for admirable individuals in the gaming industry, until this year
Rebecca Coley’s hybrid surfing feature documentary “Point of Change” will make its sales launch at AFM through Michael Ryan at Gleneagles Films. The film won best documentary feature film at the Los Angeles Film Awards, and the Committee Choice Award at the Bali Intl. Film
A Norwegian citizen was struck by a wall panel during a visit to the museum in 2022.
Donald Trump is finally acknowledging the reality of his policies.
Electricity powers our lives, including our cars, phones, computers, and more, through the movement of electrons within a circuit. While we can't see these electrons, electric currents moving through a conductor flow like water through a pipe to produce electricity.
This 'Fiddling with Fulgurating Fulminations' walkthrough helps you complete this side mision in The Outer Worlds 2 and find all lightning rod towers.
A program promoting rising stars in the video game industry has been quietly erased The post The Game Awards Deletes Its Future Class appeared first on Kotaku .
New research has confirmed that West Coast transient killer whales who live between British Columbia and California are two distinct subpopulations: inner and outer coast transients.
In his most recent video , Evan Puschak takes a close look at Marlon Brando’s face and gestures in a scene from On the Waterfront to explain how Brando changed film forever. And this is what makes Brando a genius: when his eyes betray his words. His voice says, “What do you
The man who slung a sandwich at a federal agent in Washington, D.C., and was unwittingly transformed into an opposition symbol of President Trump’s local crime crackdown has been found not guilty of misdemeanor assault after a trial. A jury handed down the not guilty verdict