Northeastern University researchers used an original machine learning tool to predict how genetic mutations cause a rare metabolic disease known as OTC deficiency, uncovering some underlying biochemical mechanisms at play and laying the groundwork for future treatments.
Fabien Frankel has signed with CAA for representation. The 31-year-old actor is best known for his role as Ser Criston Cole in HBO’s “Game of Thrones” prequel “House of the Dragon,” and he can currently be seen on the miniseries “Task,” on which he stars as FBI agent Anthony
In most developing tissues, signals called morphogens act like lighthouses, guiding nearby cells toward their fate and telling them what to become. Each cell relies on such signals for organized structures like organs and limbs to form. But as Jean-Paul Vincent explains, "for
The wife of a slain journalist wrote a letter to President Trump and the first lady urging them both to take up her calls for “justice” at his Tuesday meeting with Saudi Arabian Crown Prince Mohammed bin Salman. Hanan Elatr-Khashoggi is still lobbying for her husband’s body to
Portuguese soccer player Cristiano Ronaldo will be at the White House on Tuesday as President Trump meets with Saudi Crown Prince Mohammad bin Salman, according to a White House official. Ronaldo plays for the Saudi club al-Nassr. The soccer star’s trip to Washington also
W Hotels is officially stepping into the all-inclusive arena — but true to form, the brand isn’t merely joining the category, it’s rewriting the rules. With the grand opening of W Punta Cana, the 26-year-old lifestyle hotel marquee is reshaping a category long synonymous with
Vibrio bacteria are major pathogens in the aquaculture industry, triggering vibriosis—a disease that can cause mortality rates of up to 90% within two days. This not only results in billions of dollars in economic losses globally but also poses a threat to food safety through
President Trump welcomed Saudi Arabia's Crown Prince Mohammed bin Salman on Tuesday in an opulent ceremony complete with a military flyover in what was arguably the most elaborate arrival of a foreign leader to the White House this year. The arrival included a band, a military
A Hochul aide has reached out to finance leaders in hopes of convincing the Trump administration to refrain from deploying federal troops to the city.
A new Marvel game, Banishers, The Crew Motorfest, and more all join Xbox Game Pass in late November and early December.
Severe flooding and a massive landslide in northern Italy’s Friuli Venezia Giulia region killed two people, destroyed homes and triggered major rescue operations.
This is the most affordable 15-inch portable monitor for Black Friday. The post Portable 15-Inch Gaming Monitor Cheaper Than Budget Controller, Now Lets You Play Switch on Big Screen appeared first on Kotaku .
Banijay Americas’ BD4 documentary label has partnered with theatrical distributor Fathom Entertainment and Major League Baseball production shingle MLB Studios to produce the doc “Homecoming: The Tokyo Series,” which is set to premiere in movie theaters on February 23 and 24.
Sinners director Ryan Coogler has confirmed he's directing Black Panther 3 for Marvel Studios, possibly coming in 2028.
We know—and love—the Turtle Rescue Team here at The Abstract. But their work isn't just limited to our shelled friends: snakes are sometimes visitors to the TRT as well. In a recent study published in the Journal of Zoo and Wildlife Medicine, Greg Lewbart, professor of aquatic,
If you’re in the market for a new machine or an accessory for your existing PlayStation, Sony's got some nice deals The post The PS5 Will Be As Cheap As It Was 5 Years Ago For Black Friday appeared first on Kotaku .
President Trump on Tuesday welcomed Saudi Arabia’s Crown Prince Mohammed bin Salman to the White House with an arrival ceremony on a grand scale along the South Lawn, the most elaborate arrival of a foreign leader to the White House during the second Trump administration. A
Sundar Pichai, head of Google parent company Alphabet, said he sees “elements of irrationality” in the AI boom, amid concerns of a market pullback. In an interview with the BBC, Pichai called this an “extraordinary moment” for artificial intelligence but said the excitement
[Nile Post] Several entrepreneurs and ten global business leaders of African descent have urged young people to take responsibility for their future by embracing innovation and entrepreneurship.
Getting a lot of heat—literally.
The winners of the LIT Lighting Design Awards , encompassing the best work in lighting architecture, product design (lamps, etc.), concerts, healthcare, streets, and many more categories. 💬 Join the discussion on kottke.org →
Get your PC purchases in ASAP, peeps.
It's a great chance to convert your non-Battlefield 6 playing friends.
A new paper by evolutionary anthropologists Colin Shaw (University of Zurich) and Daniel Longman (Loughborough University) argues that modern life has outpaced human evolution. The study suggests that chronic stress and many modern health issues are the result of an
A federal appeals court on Tuesday refused President Trump’s attempt to revive his dismissed defamation lawsuit against CNN for describing his baseless claims of mass election fraud in 2020 as the “Big Lie.” The 11th U.S. Circuit Court of Appeals panel agreed with a lower
KYIV - Ukraine's military said on Tuesday it had attacked military targets in Russia with U.S.-supplied ATACMS missiles, calling it a \"significant development.\"
One of the world's most popular gaming platforms has faced criticism for its child safety record.
Catch up with the most important stories from around Europe and beyond this November 18th, 2025 - latest news, breaking news, World, Business, Entertainment, Politics, Culture, Travel.
Oz has never felt more great and powerful than it does in “Wicked: For Good.” Where the first entry in director Jon M. Chu’s exuberant two-parter succeeded in wowing audiences last fall, its more familiar follow-up delivers what we might call the “whew factor,” as in: Thank
NBCUniversal and the Television Academy are ahead of schedule, announcing an 2026 Emmy date much earlier than usual. The TV Academy hasn’t yet unveiled next year’s Emmy calendar, but it already has a date for the ceremony: Monday, Sept. 14, 2026 at 8 p.m. ET/5 p.m. PT. The move
Overall, Ukrainians seem determined to keep fighting and unwilling to beg for a ceasefire.
Optical quantum computers are gaining attention as a next-generation computing technology with high speed and scalability. However, accurately characterizing complex optical processes, where multiple optical modes interact to generate quantum entanglement, has been considered
ATLANTA — Gov. Kathy Hochul (D) says she’s ready to work with Mayor-elect Zohran Mamdani, even though she doesn’t agree with all of his policies. Their earliest point of friction, for example, is his proposal for “fast and free” city buses. But she told "Raising America" that
A new paper by University of Rhode Island post-doctoral researchers Emily Sperou and Renato Borras-Chavez published in the journal Polar Biology discusses a unique phenomenon observed in a reclusive Antarctic animal: postmortem attentive behavior, or PAB, in the solitary
These are the stocks posting the largest moves midday.
When the COVID-19 pandemic hit in 2020, schools around the globe had to switch from regular, in-person classes to online learning overnight. This introduced numerous operational challenges, particularly in equipping students with quantitative skills essential for the labor
Determining the least expensive path for a new subway line underneath a metropolis like New York City is a colossal planning challenge—involving thousands of potential routes through hundreds of city blocks, each with uncertain construction costs. Conventional wisdom suggests
"They took Opryland from me, so I’m going to bring it back," the comedian previously said about the now-developing project
Also: The Epic Store gets a nifty new feature, Valve says Steam Machines are better than most PCs, Roblox rolls out face scanning, and KPop Demon Hunters come to the Macy's Day Parade The post No, The Game Awards Aren’t Rigged appeared first on Kotaku .
What are they doing over there in Iowa? Every year, the Hinterland Festival comes to the Des Moines area. When it started in 2015, the fest went heavy on roots music and indie rock, but it has slowly evolved into something else. At this year's fest , the headliners were Lana
Metabolic engineering has enabled the construction of efficient microbial cell factories, but cellular aging and the accumulation of toxic metabolites during prolonged fed-batch fermentation induce metabolic stress, which ultimately reduces cell productivity. Extending cellular
President Trump took a verbal jab last week at a reporter asking a question about files tied to convicted sex offender Jeffrey Epstein while aboard Air Force Once, an incident getting renewed attention as the House is set to vote on legislation forcing the release of the