Researchers have revealed that so-called “junk DNA” contains powerful switches that help control brain cells linked to Alzheimer’s disease. By experimentally testing nearly 1,000 DNA switches in human astrocytes, scientists identified around 150 that truly influence gene
Between smash-hit movies, ongoing classics, and new revelations, anime had another great year in 2025. Here are the best 25, selected by Polygon.
A large-scale model study now shows how the global food system can contribute to the fight against global warming. It identifies 23 levers, calculates their effectiveness and concludes: a decisive transformation of this sector alone, without the indispensable energy transition,
The Kansas City Chiefs are the undisputed NFL team of choice for Swifties — but the team’s ultimate goal is total world fandom domination. Following the success of the 2024 Hallmark Channel Christmas movie “Holiday Touchdown: A Chiefs Love Story” — a rom-com loosely inspired by
Savory Rice Krispies treats? “Savory chicken fat and fried onions push Rice Krispies Treats into gloriously salty-sweet territory.” 💬 Join the discussion on kottke.org →
The fast-fashion giant welcomed the judgement and said its priority remains protecting French consumers.
Nigeria is on display in a softer light as residents of Lagos gathered to see the city’s Christmas decorations.
The Avengers: Doomsday teaser reveals Chris Evans reprising his role as Steve Rogers, now a proud father, hinting at his return to the MCU
Kristin Cabot told The New York Times that she's faced harassment since a clip of the incident went viral this summer.
Prominent conservative voices clashed on Thursday at Turning Point USA’s annual AmericaFest conference, as Ben Shapiro criticized Tucker Carlson for hosting controversial guests such as white nationalist Nick Fuentes and divisive influencer Andrew Tate on his show. Shapiro
The actor chalked up his gaunt appearance to a stomach bug, exacerbated by his ongoing cancer battle, in a new interview
A full walkthrough for the A Toxic Trail quest in Arc Raiders including where to go on Dam Battlegrounds and where to find the source.
Allow me to pull the curtain back on the way that this particular website operates during the holidays. Once we finalize all our year-end lists, things tend to get way slower around here, and Scott lets us take most of late December off. But someone is always working. Scott is
A full walkthrough for the 'Paving The Way' quest in Arc Raiders including how to find an Enelica building and where the Convinio is in Piazza Roma.
"I would like to play it and see what they wind up doing."
More than $900 million in Federal Emergency Management Agency (FEMA) grants and loans are awaiting Homeland Security Secretary Kristi Noem’s approval under her controversial policy of personally reviewing major expenditures, an agency source told The Hill. This represents a
In a rare and historic achievement, Children’s Hospital Colorado successfully completed its first dual heart and liver transplant in a pediatric patient. The life-saving surgery was performed on 11-year-old Gracie Greenlaw, whose congenital heart condition eventually led to
Nike stock plunged nearly 10% after the sneaker giant reported sliding profits due to an anticipated $1.5 billion hit from tariffs as well as a slowdown in China.
An easy way to cook dinner for busy people. The post Forget Ninja, Breville Is Basically Giving Away Its Smart Oven Air Fryer After Cutting Coffee Machines appeared first on Kotaku .
A team of researchers affiliated with UNIST has made a significant breakthrough by mathematically proving that a special type of vortex pair, called the Sadovskii vortex patch, can exist within ideal fluid flows. This marks the first time such a solution has been rigorously
The video rapidly racked up more than 12 million views after it was shared on Facebook.
Mette-Marit has pulmonary fibrosis, a disease that stiffens the lungs, making it hard to breathe.
It’s time to return to Pandora because James Cameron’s “Avatar: Fire and Ash” is here. The third “Avatar” movie has made $12 million in domestic previews at the box office. In international markets, it grossed $43.1 million from 43 markets. “Fire and Ash” is expected to lead
Warm dense matter is a state of matter that forms at extreme temperatures and pressures, like those found at the center of most stars and many planets, including Earth. It also plays a role in the generation of Earth's magnetic field and in the process of nuclear fusion.
[Nile Post] Uganda's ratification of a new African Union protocol recognising social protection and social security as enforceable rights is a "historic milestone", civil society groups said on Friday, while warning that major funding and coverage gaps threaten to blunt its
South Park seasons 27 and 28 didn't just trash Trump, they were also the most nostalgic ever
The Colorado River Compact was negotiated in 1922 to end the fighting over the river's use, and the current round of negotiations is just as important, as more than 40 million people rely on the river for water security, and the Upper Basin states have put forward serious
These game designers say Portal is the most influential game of all-time. Do you agree?
Using insects such as wasps to control agricultural pests remains a resilient method, despite increasing resistance, a new University of Stirling study has shown.
The more details that emerge about Jeffrey Epstein and Donald Trump, the clearer it is that the two shared a wildly unconventional—and creepy—relationship. Hours after The New York Times reported Thursday that Epstein and Trump bonded over “ trophy hunting, ” investigative
A vigil for those trampled in the name of profits.
When can you go to the bathroom during Avatar 3? Check our chart. But definitely don't leave during James Cameron's trolling pee-break gag.
The benefits of environmental protection, measured in terms of advancing public health and the economy, outweigh the costs associated with implementing and enforcing environmental regulations, according to researchers at Penn State who published a new perspective piece in the
[African Union] The Chairperson of the African Union Commission, H.E. Mahmoud Ali Youssouf, received the Members of the AU Panel of the Wise at AU Headquarters for an exchange on preventive diplomacy, peace and security reforms, and emerging challenges across the continent. He
Elegant and primed for flight, these birds perch between abstract and realistic representations. Do stories and artists like this matter to you? Become a Colossal Member today and support independent arts publishing for as little as $7 per month. The article Anthony Theakston
The extraction shooter is 20 percent off, just a couple of months since its release The post Arc Raiders Is On Sale For The First Time Since Launch appeared first on Kotaku .
