X-ray laser offers new look at protein movement inside cells

At European XFEL, researchers have observed in detail how the vital iron protein ferritin makes its way in highly dense environments—with implications for medicine and nanotechnology.

How cancer cells keep their chromosomes intact to continue dividing relentlessly

Scientists at Children's Medical Research Institute (CMRI) have made a major discovery about cancer cells. This new understanding could help make chemotherapy work better, reduce side effects, and lead to the development of new cancer treatments.

NBC News Launches Ad-Free Subscription Streaming Service Offering ‘Dateline,’ ‘Today,’ Podcasts, More

Under the supervision of executive Cesar Conde, NBC News has rolled out a long suite of streaming products that offer digitally savvy news aficionados access to “Today,” “Dateline” and more. Now, the company will offer all of its content in a single basket. The new service will

I Have No Idea Who Would Actually Want This $300 Stranger Things Set

While I'm not excited about owning The Creel House, all those minifigs seem great The post I Have No Idea Who Would Actually Want This $300 Stranger Things Set appeared first on Kotaku .

Chappell Roan, Mariah Carey, 50 Cent Among ‘Dick Clark’s New Year’s Rockin’ Eve’ Performers

Charlie Puth, 4 Non Blondes and the singing voices from Kpop Demon Hunters also make up the line-up

Trump administration puts Fema workers back on administrative leave

Fourteen workers who signed a petition that warned cuts put the US at risk were initially suspended in August The Trump administration is reversing the reinstatement of workers at the Federal Emergency Management Agency (Fema) who were placed on administrative leave after

Newly discovered viral enzymes act like molecular scissors to disable immune alarm signals

Viruses and their hosts—whether bacteria, animals, or humans—are locked in a constant evolutionary arms race. Cells evolve defenses against viral infection, viruses evolve ways around those defenses, and the cycle continues.

Fabergé's rare Winter Egg fetches record £22.9 mn at auction

Fabergé's The Winter Egg, considered one of his most beautiful creations, sold for nearly £23 million ($30 million) at auction Tuesday in London, smashing the sales record for the legendary jeweler of Imperial Russia.

Michelangelo Drawing of a Foot Could Fetch $2M at Auction

The newly discovered five-inch sketch dates back 500 years.

Elden Ring Nightreign Forsaken Hollows release date and time revealed

Elden Ring Nightreign DLC The Forsaken Hollows is out on Dec. 4, but depending on your time zone, you may access it earlier. Here's how.

Mark Zuckerberg’s Instagram orders workers back to office 5 days per week

Mark Zuckerberg’s Instagram is requiring all of its US-based employees to return to the office five days per week, a company spokesperson confirmed on Tuesday.

Woodland Puppets Sing an Ode to Friendship in Apple’s Refreshingly Analog Holiday Ad

Titled "A Critter Carol," the short film takes its cues from compassion, creativity, and community. Do stories and artists like this matter to you? Become a Colossal Member today and support independent arts publishing for as little as $7 per month. The article Woodland

Orange juice found to affect thousands of genes in immune cells, study says

A significant number of these genes are involved in mechanisms that regulate blood pressure, reduce inflammation and control sugar metabolism. These are critical processes for long-term cardiovascular health.

Cynthia Erivo Reopens Plaza Theatre in Palm Springs With Bravura Performance, After Regaining Lost Voice in the Nick of Time: Concert Review

Finding the ideal artist to reopen the historic Plaza Theatre in Palm Springs might have seemed like a tall order, at least if the 89-year-old venue’s new operators wanted to touch every possible important base for a refurbishment-celebrating gala. Someone whose concert

OpenAI’s Sam Altman declares ‘code red’ to improve ChatGPT as Google catches up: reports

OpenAI boss Sam Altman has reportedly declared a “code red” pushing employees to improve ChatGPT as AI giant fends off concerns that it is losing ground to rivals like Google.

Chimpanzee calls trigger unique brain activity in humans, revealing shared vocal processing skills

The brain doesn't just recognize the human voice. A study by the University of Geneva (UNIGE) shows that certain areas of our auditory cortex respond specifically to the vocalizations of chimpanzees, our closest cousins, both phylogenetically and acoustically.

‘Stranger Things 5’ Opens With 59.6 Million Views, Netflix’s Biggest English-Language TV Debut Ever

“Stranger Things” Season 5 had a record-breaking debut on Netflix. In its first five days of streaming, the season achieved 59.6 million views. That’s the best premiere-week viewership an English-language Netflix series has ever achieved, and the third-best overall, coming

GameStop celebrates $30k trade-in by calling its critics "trolls"

A historic trade-in worth $30,000 isn't really indicative of how much customers will get for their wares at GameStop, despite what the retailer says

EFF Tells Patent Office: Don’t Cut the Public Out of Patent Review

EFF has submitted its formal comment to the U.S. Patent and Trademark Office (USPTO) opposing a set of proposed rules that would sharply restrict the public’s ability to challenge wrongly granted patents. These rules would make inter partes review (IPR)—the main tool Congress

Retrospekt refurbs and sells retro technology (VHS tapes, cassette players, instant cameras,...

Retrospekt refurbs and sells retro technology (VHS tapes, cassette players, instant cameras, typewriters, iPods). 💬 Join the discussion on kottke.org →

The Marathon art theft debacle has been 'resolved to my satisfaction,' according to the artist Bungie stole from

Bungie has apparently done right by the artist it stole from to develop Marathon's look.

Pressley passes on Massachusetts Senate bid, vies for reelection instead

Rep. Ayanna Pressley (D-Mass.), a member of the progressive “Squad,” said Tuesday that she’s passing on a Senate bid for Sen. Ed Markey’s (D-Mass.) seat and will instead run for reelection in Massachusetts's 7th Congressional District. “Ultimately in this moment, I feel called

Trump Team Breaks Out in Applause as He Calls Ilhan Omar “Garbage”

President Trump used the last few minutes of his hours-long Cabinet meeting Tuesday to launch a particularly nasty attack on Democratic Representative Ilhan Omar and the entire country of Somalia. Trump’s rant was spurred by a leading question about Minnesota governor and

Luna pushes to force a vote banning congressional stock trading

Larry Summers banned for life from prestigious economist club over Jeffrey Epstein scandal

The Nashville-based nonprofit said it had permanently revoked Summers's membership and blacklisted the former Treasury Secretary under Bill Clinton from all of its work.

Toxoplasmosis: How a deadly parasite infects its host cells

Researchers at LMU in collaboration with the European Molecular Biology Laboratory (EMBL) in Heidelberg have discovered how the parasite Toxoplasma gondii builds a specialized structure that allows it to move and invade host cells. The study, published in Nature Communications,

French journalist unions file legal complaint accusing Israel of obstructing press freedom

The complaint filed with France’s anti-terror prosecutor accuses Israeli authorities of systematic obstruction and war crimes against reporters.

ESPN's Paul Finebaum says he won't run for Alabama Senate seat

ESPN's Paul Finebaum says he will not run to replace Sen. Tommy Tuberville (R) in the Senate, ending months of speculation that the sports media personality could make a foray into politics. “I have been deeply moved by so many people in Alabama who have reached out encouraging

Sickos hack 120K home security cameras in South Korea, sell off sexually explicit footage: authorities

The hack is the latest in a global trend targeting internet protocol cameras, often used in homes to keep an eye on children and pets, as well as in businesses, hospitals and saunas.

All unlockable champions in Teamfight Tactics Set 16: Lore and Legends

Teamfight Tactics Set 16's main mechanic is Unlocks. 40 champions are locked behind specific objectives. Here's how to unlock them all.

These Bat Buddies Sound Eerily Alike

Female vampire bats start to mimic each other over time, offering an intriguing hint into intimate animal social circles The post These Bat Buddies Sound Eerily Alike appeared first on Nautilus .

Chance discovery converts toxic nitric oxide into nitrogen gas at room temperature

Nitrogen is a crucial component of proteins and nucleic acids, the fundamental building blocks of all living things, and thus is essential to life on Earth. Gaseous N2 from the atmosphere can be fixed by soil bacteria capable of converting N2 to ammonia or nitrates (NO3).

National Guard shooting suspect hit with murder, assault charges

Related video: DC Bureau: Immigration Changes after National Guard Shooting The man accused of shooting two National Guard members in Washington, D.C., killing one of them, has been formally charged with offenses including murder and assault, court filings show. Rahmanullah

Pope Leo Warns Trump Against Military Intervention in Venezuela

Pope Leo has implored Donald Trump not to use military force to force out Venezuelan President Nicolás Maduro. The first American leader of the Catholic Church told reporters Tuesday that it would be “ better ” to “find another way” to apply pressure, such as hosting a dialogue

Iran uses first joint SCO field drills to tout drone power, assert post-war resilience

The five-day drill includes participation from China, Russia, India, Pakistan, Belarus, Kazakhstan, Kyrgyzstan, Tajikistan and Uzbekistan. Observer states Saudi Arabia, Azerbaijan and Iraq will also be present.

Rapid weather shifts govern how plants influence climate and air quality, study finds

A new study shows that during drought, it's not how hot or how dry it is that determines gas emissions from plants—but how quickly conditions change. This discovery reshapes our understanding of the relationship between drought, vegetation, and air pollution.

Indonesia to repatriate two convicted Dutch drug traffickers, including one on death row

The United Nations Office on Drugs and Crime says Indonesia is a major drug smuggling hub despite having some of the strictest drug laws in the world.

‘Vanderpump Rules’ Season 12: How to Watch the Reboot Online

“Vanderpump Rules” fans will officially be introduced to a new crew of SUR staffers on Tuesday night. Bravo’s Emmy-winning reality show returns for its 12th season on Dec. 2 at 9 p.m. ET. The best way for cable-cutters to tune into the premiere is on Sling TV, whose Sling Blue

Optical clock sets new accuracy record, bringing us closer to a new definition of the second

A research team at VTT MIKES has set a new record in optical-clock absolute frequency measurements using a strontium single-ion clock with exceptionally low uncertainty and high uptime.

Shovel Knight developer Yacht Club Games will be in serious trouble if its next release isn't a hit: 'It's make-or-break for sure'

Mina the Hollower was supposed to be out at the end of October but was delayed at the last minute, and does not have a new release date.

Sam Worthington Weighs in on Future of ‘Avatar’ After ‘Fire and Ash’: “To Me, This Was Always the Final Battle”

The third film in James Cameron's groundbreaking franchise premiered in L.A., after the filmmaker said he'd be willing to walk away from his planned fourth and fifth movies if it's not a box office breakout.

What to know about Rahmanullah Lakanwal, suspect in National Guard shooting

Related video: DC Bureau: Immigration Changes after National Guard Shooting Two members of the West Virginia National Guard were shot close to the White House last week, sparking outrage from the political right and a crackdown on immigration from the Trump administration. The

Delayed tariff impact starting to hit, could cause companies to reduce head count in 2026

President Trump's tariffs, aimed at reshoring American jobs lost to overseas manufacturing, could end up lowering head count instead

Global heating and other human activity are making Asia’s floods more lethal

Much improved response systems are struggling to cope with ever more powerful and destructive storms Death toll from Indonesia floods passes 700 as 1 million evacuated Families stranded on their rooftops. Homes buried by fast-flowing mud. Jagged brown craters scarring lush

‘Mad Men’ Hits HBO Max With Goofy Errors, Including Visible Barf Machine Operators

Along with mislabeled episodes, crew members can be seen in the background of a Season One episode as Roger Sterling pukes on the carpet of Sterling Cooper

Adjustable DNA 'shield' can control timing and rate at which mRNA produces proteins in vivo

mRNA, widely known from the COVID-19 vaccine, is not actually a "therapeutic agent," but a technology that delivers the blueprint for functional proteins in the body and induces therapeutic effects. Recently, its application has expanded to cancer and genetic disease

Kraft, Coca-Cola among companies sued by San Francisco over ultra-processed foods in first-of-a-kind lawsuit

The lawsuit marks the first time a municipality has sued over claims food companies have knowingly marketed addictive and harmful ultra-processed foods.

GOP senator: Trump pardon of convicted Honduran president sends 'horrible message'

Sen. Thom Tillis (R-N.C.) said that President Trump’s controversial decision to pardon former Honduran President Juan Orlando Hernandez, who was serving a 45-year sentence for conspiring to import cocaine, sends a “horrible message.” Tillis, a member of the Senate Judiciary

Gary Dauberman Signs With WME (Exclusive)

The triple threat wrote the 'It' movies, directed 'Annabelle Comes Home' and is producing 'The Revenge of La Llorona.'

Attn Drew Carey: Phish Are Returning To Sphere

In the spring of 2024, the world-renowned jam band Phish became one of the first musical acts to play a residency at Sphere Las Vegas, the high-tech Vegas venue owned by New York Knicks owner James Dolan. The Price Is Right host Drew Carey went to one of those gigs, and he was